Comment: In Response to “Megaloblastic Anemia with Ring Sideroblasts is not Always Myelodysplastic Syndrome”
نویسنده
چکیده
6. Rakic S, Belic B, Erceg S, Jovanovic R, Kulic Z, Stefanovic N, Belic A, Uzurov V, Spasojevic J. Complications in the use of blood transfusions-alloimmunization in polytransfused patients. Med Pregl 1999;52:375378. 7. Sanz C, Nomdedeu M, Belkaid M, Martinez I, Nomdedeu B, Pereira A. Red blood cell alloimmunization in transfused patients with myelodysplastic syndrome or chronic myelomonocytic leukemia. Transfusion 2013;53:710-715.
منابع مشابه
Diagnosis and Management of Anemia in Patients With the Myelodysplastic Syndrome.
Myelodysplastic syndrome (MDS) is composed of a group of diseases that for decades have been challenging to diagnose and manage. MDS is a clonal disease of the bone marrow. The pathologic manifestation of morphologic abnormalities (dysplasia) include ringed sideroblasts, megaloblastic changes, pseudo-Pelger cells, and micromega and multinucleated megakaryocytes. The clinical spectrum ranges fro...
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Ring sideroblasts Ring sideroblasts are erythroblasts with iron-loaded mitochondria visualized by Prussian blue staining (Perls’ reaction) as a perinuclear ring of blue granules (Figures 1D and 2C). The International Working Group on Morphology of Myelodysplastic Syndrome (IWGM-MDS) recommended that ring sideroblasts be defined as erythroblasts in which there are a minimum of five siderotic gra...
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Introduction: The Thiamine Transporter gene SLC19A2 is the only gene known to be associated with TRMA. This syndrome is a trial clinical characterized by megaloblastic anemia, nonautoimmune diabetes mellitus and sensory-neural hearing loss. Methods: Described here are three children from consanguineous Iranian families with thiamine – responsive megaloblastic anemia (TRMA) or Rogers' syndrome....
متن کاملClinical management of myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes
The myelodysplastic/myeloproliferative neoplasms (MDS/MPNs) are a unique group of hematologic malignancies characterized by concomitant myelodysplastic and myeloproliferative features. According to the 2008 WHO classification, the category includes atypical chronic myeloid leukemia (aCML), chronic myelomonocytic leukemia (CMML), juvenile myelomonocytic leukemia (JMML), MDS/MPN-unclassifiable (M...
متن کاملAn Active Isodicentric X Chromosome in a Case of Refractory Anaemia with Ring Sideroblasts Associated with Marked Thrombocytosis
Refractory anaemia with ring sideroblasts and marked thrombocytosis (RARS-T) is a provisional entity in the World Health Organization (WHO) classification. It displays features characteristic of both myelodysplastic syndrome and myeloproliferative neoplasia plus ring sideroblasts ≥15% and marked thrombocytosis. Most patients with RARS-T show a normal karyotype. We report a 76-year-old woman dia...
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عنوان ژورنال:
دوره 33 شماره
صفحات -
تاریخ انتشار 2016